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Welcome at the web site of the Institute for Computational Systems Biology in Hamburg headed by Prof. Dr. Jan Baumbach

CoSy.Bio is a research laboratory that investigates the molecular mechanisms driving diseases using artificial intelligence methodology and combinatorial optimization. It is located with the Chair of Computational Systems Biology at the University of Hamburg.

We develop computational methods for Network and Systems Medicine, in particular for mechanotyping and redefining diseases by their mechanistic causes rather than symptoms. Here, we emerge novel ways for drug repurposing and synergistic pharmacology.

We also develop privacy-preserving artificial intelligence tools to unleash the power of big data in precision medicine, where sensitive data may not be shared cross-institutionally for prediction model learning. We thus develop privacy-by-design methods, largely based on federated artificial intelligence, that respect individual privacy while still allowing for big data analytics. 






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